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# CITATION file created with {cffr} R package
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cff-version: 1.2.0
message: 'To cite package "DANDELION" in publications use:'
type: software
license: GPL-3.0-only
title: 'DANDELION: Discovery of Candidate Disease Genes Using Trans-Regulatory Effects'
version: 0.1.0
doi: 10.32614/CRAN.package.DANDELION
abstract: Implements the DANDELION method for prioritizing candidate disease-related
  proximal genes by integrating trans-regulatory association p-values and gene-level
  trait association p-values. The statistical testing framework builds on the divide-aggregate
  composite-null test described by Liu et al. (2022) <https://doi.org/10.1080/01621459.2021.1914634>.
  The biological application and SNP/gene-based prioritization workflow are motivated
  by Salamone et al. (under review), "Leveraging trans-gene regulation prioritizes
  central genes and pathways in asthma". The package provides functions for identifying
  distal-proximal gene pairs, organizing significant pairs into genomic loci, and
  visualizing resulting gene networks.
authors:
- family-names: Tian
  given-names: Peixin
  email: pxtian@connect.hku.hk
repository: https://mxxptian.r-universe.dev
commit: b681ba94e6de30641a3d2b98bfc3d9bdb0775f5b
date-released: '2026-05-07'
contact:
- family-names: Tian
  given-names: Peixin
  email: pxtian@connect.hku.hk